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Romifidine

Catalog No. T26119 CAS 65896-16-4

Synonyms: Romifidinum

Romifidine is used as a sedative in veterinary medicine mainly in large animals such as horses. It acts as an agonist at the α2 adrenergic receptor subtype.

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Romifidine, CAS 65896-16-4

Pack Size	Availability	Price/USD	Quantity
100 mg	6-8 weeks	$ 823.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Romifidine is used as a sedative in veterinary medicine mainly in large animals such as horses. It acts as an agonist at the α2 adrenergic receptor subtype.

Synonyms	Romifidinum
Molecular Weight	258.09
Formula	C9H9BrFN3
CAS No.	65896-16-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Gómez-Villamandos RJ, Martínez C, Navarrete R, Morgaz J, Domínguez JM, López I, Muñoz P, Fernández A, Granados MM. Romifidine and low doses of tiletamine-zolazepam in dogs. Vet Anaesth Analg. 2013 Nov;40(6):e40-7. doi: 10.1111/vaa.12054. Epub 2013 Jun 20. PubMed PMID: 23782643. 2. Marly C, Bettschart-Wolfensberger R, Nussbaumer P, Moine S, Ringer SK. Evaluation of a romifidine constant rate infusion protocol with or without butorphanol for dentistry and ophthalmologic procedures in standing horses. Vet Anaesth Analg. 2014 Sep;41(5):491-7. doi: 10.1111/vaa.12174. Epub 2014 May 17. PubMed PMID: 24835127. 3. de Vries A, Pakkanen SA, Raekallio MR, Ekiri A, Scheinin M, Taylor PM, Vainio OM. Clinical effects and pharmacokinetic variables of romifidine and the peripheral α(2) -adrenoceptor antagonist MK-467 in horses. Vet Anaesth Analg. 2016 Nov;43(6):599-610. doi: 10.1111/vaa.12354. Epub 2016 Feb 26. PubMed PMID: 26918855. 4. Costa GL, Cristarella S, Quartuccio M, Interlandi C. Anti-nociceptive and sedative effects of romifidine, tramadol and their combination administered intravenously slowly in ponies. Vet Anaesth Analg. 2015 Mar;42(2):220-5. doi: 10.1111/vaa.12210. Epub 2014 Jul 21. PubMed PMID: 25039663.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Romifidine 65896-16-4 Romifidinum inhibitor inhibit

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