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Renzapride hydrochloride

Catalog No. T28517 CAS 109872-41-5

Synonyms: BRL-24924, ATL1251, ATL-1251, Renzapride HCl, AZM-112

Renzapride is a 5-HT3 antagonist and 5-HT4 agonist. Renzapride also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors.

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Renzapride hydrochloride Chemical Structure

Renzapride hydrochloride, CAS 109872-41-5

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,670.00
50 mg	6-8 weeks	$ 2,180.00
100 mg	6-8 weeks	$ 2,800.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Renzapride is a 5-HT3 antagonist and 5-HT4 agonist. Renzapride also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors.

Synonyms	BRL-24924, ATL1251, ATL-1251, Renzapride HCl, AZM-112
Molecular Weight	360.28
Formula	C16H23Cl2N3O2
CAS No.	109872-41-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Mozaffari S, Nikfar S, Abdollahi M. Efficacy and tolerability of renzapride in irritable bowel syndrome: a meta-analysis of randomized, controlled clinical trials including 2528 patients. Arch Med Sci. 2014 Feb 24;10(1):10-8. doi: 10.5114/aoms.2014.40729. Epub 2014 Feb 23. Review. PubMed PMID: 24701208; PubMed Central PMCID: PMC3953973. 2. Ford AC. Renzapride in IBS: is efficacy in the eye of the beholder? Aliment Pharmacol Ther. 2010 Jul;32(1):113-4; author reply 114-5. doi: 10.1111/j.1365-2036.2010.04275.x. PubMed PMID: 20597877. 3. Lembo AJ, Cremonini F, Meyers N, Hickling R. Clinical trial: renzapride treatment of women with irritable bowel syndrome and constipation - a double-blind, randomized, placebo-controlled, study. Aliment Pharmacol Ther. 2010 May;31(9):979-90. doi: 10.1111/j.1365-2036.2010.04265.x. Epub 2010 Feb 16. PubMed PMID: 20163375. 4. Scarpellini E, Tack J. Renzapride: a new drug for the treatment of constipation in the irritable bowel syndrome. Expert Opin Investig Drugs. 2008 Nov;17(11):1663-70. doi: 10.1517/13543784.17.11.1663 . Review. PubMed PMID: 18922103.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Renzapride hydrochloride 109872-41-5 AZM112 BRL 24924 ATL 1251 Renzapride Hydrochloride BRL-24924 ATL1251 BRL24924 AZM 112 ATL-1251 Renzapride HCl AZM-112 inhibitor inhibit

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