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Renin inhibitory peptide

Catalog No. TP2351 CAS 75645-19-1

Synonyms: Pro-his-pro-phe-his-phe-phe-val-tyr-lys

Renin inhibitory peptide is an analog of angiotensinogen.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Renin inhibitory peptide Chemical Structure

Renin inhibitory peptide, CAS 75645-19-1

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Renin inhibitory peptide is an analog of angiotensinogen.

Synonyms	Pro-his-pro-phe-his-phe-phe-val-tyr-lys
Molecular Weight	1318.52
Formula	C69H87N15O12
CAS No.	75645-19-1

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Fitzgerald C, Aluko RE, Hossain M, Rai DK, Hayes M. Potential of a renin inhibitory peptide from the red seaweed Palmaria palmata as a functional food ingredient following confirmation and characterization of a hypotensive effect in spontaneously hypertensive rats. J Agric Food Chem. 2014 Aug 20;62(33):8352-6. doi: 10.1021/jf500983n. Epub 2014 Aug 7. PubMed PMID: 25062358. 2. Fitzgerald C, Mora-Soler L, Gallagher E, O'Connor P, Prieto J, Soler-Vila A, Hayes M. Isolation and characterization of bioactive pro-peptides with in vitro renin inhibitory activities from the macroalga Palmaria palmata. J Agric Food Chem. 2012 Aug 1;60(30):7421-7. doi: 10.1021/jf301361c. Epub 2012 Jul 19. PubMed PMID: 22747312. 3. Thaisrivongs S, Pals DT, DuCharme DW, Turner SR, DeGraaf GL, Lawson JA, Couch SJ, Williams MV. Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys. J Med Chem. 1991 Feb;34(2):633-42. PubMed PMID: 1995887. 4. Lafarga T, Rai DK, O'Connor P, Hayes M. A Bovine Fibrinogen-Enriched Fraction as a Source of Peptides with in Vitro Renin and Angiotensin-I-Converting Enzyme Inhibitory Activities. J Agric Food Chem. 2015 Oct 7;63(39):8676-84. doi: 10.1021/acs.jafc.5b03167. Epub 2015 Sep 28. PubMed PMID: 26373334.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Renin inhibitory peptide 75645-19-1 Pro-his-pro-phe-his-phe-phe-val-tyr-lys inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.