Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ralaniten triacetate (EPI-506) is a novel pro-drug of Ralaniten, functioning as an orally active inhibitor of the androgen receptor (AR) N-terminal domain (NTD). Its remarkable first-in-class status signifies its unique nature within the field. This compound exhibits significant efficacy against various AR species, including AR-v7, which are associated with resistance. Notably, Ralaniten triacetate's activity encompasses full-length AR as well [1][2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 165.00 | |
5 mg | In stock | $ 413.00 | |
10 mg | In stock | $ 689.00 | |
25 mg | In stock | $ 1,490.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 473.00 |
Description | Ralaniten triacetate (EPI-506) is a novel pro-drug of Ralaniten, functioning as an orally active inhibitor of the androgen receptor (AR) N-terminal domain (NTD). Its remarkable first-in-class status signifies its unique nature within the field. This compound exhibits significant efficacy against various AR species, including AR-v7, which are associated with resistance. Notably, Ralaniten triacetate's activity encompasses full-length AR as well [1][2]. |
In vitro | Ralaniten triacetate (EPI-506) is designed to specifically target the N-terminal domain (NTD) of the androgen receptor (AR), serving as a pioneering treatment option in metastatic castration-resistant prostate cancer (mCRPC) research. As a first-of-its-kind, highly specific small molecule, EPI-506 operates by directly inhibiting AR transcriptional activity. It achieves this through binding to the AR's novel target site, the NTD, thereby preventing the AR's interaction with transcriptional proteins[2]. |
Molecular Weight | 521 |
Formula | C27H33ClO8 |
CAS No. | 1637573-04-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (191.94 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Ralaniten triacetate 1637573-04-6 Ralaniten Triacetate Ralaniten inhibitor inhibit