Home Tools
Log in
Cart

Radezolid

Catalog No. T16718   CAS 869884-78-6
Synonyms: RX-1741

Radezolid (RX-1741) is a novel oxazolidinone antibiotic agent.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Radezolid Chemical Structure
Radezolid, CAS 869884-78-6
Pack Size Availability Price/USD Quantity
1 mg In stock $ 68.00
5 mg In stock $ 167.00
10 mg In stock $ 283.00
25 mg In stock $ 483.00
50 mg In stock $ 691.00
100 mg In stock $ 983.00
1 mL * 10 mM (in DMSO) In stock $ 183.00
Bulk Inquiry
Get quote
Select Batch  
Purity: 98.06%
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description Radezolid (RX-1741) is a novel oxazolidinone antibiotic agent.
In vitro Radezolid displays a greater potency than linezolid, independent of the bacteria tested, when concentrations are expressed on a weight (mg/L) basis. Radezolid shows an improved potency compared to that of linezolid when concentrations are expressed on a weight (mg/L) basis. Radezolid MICs are systematically equal to or lower (up to 3 log2 dilutions) compared to those of linezolid for all linezolid-susceptible strains, with an 8-fold difference for the linezolid-resistant strains. Radezolid and TR-700 perform well against 3-copy G2447T, G2576T, and G2576T/T2571C mutants [1][2].
Synonyms RX-1741
Molecular Weight 438.45
Formula C22H23FN6O3
CAS No. 869884-78-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (57.02 mM)

TargetMolReferences and Literature

1. Lemaire S, et al. Cellular pharmacodynamics of the novel biaryloxazolidinone radezolid: studies with infected phagocytic and nonphagocytic cells, using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila. 2. Locke JB, et al. Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations. Antimicrob Agents Chemother. 2010 Dec;54(12):5337-43.

Related compound libraries

This product is contained In the following compound libraries:
ReFRAME Related Library NO PAINS Compound Library Bioactive Compound Library Anti-Bacterial Compound Library Anti-Infection Compound Library Preclinical Compound Library Antibiotics Library Clinical Compound Library Drug Repurposing Compound Library Bioactive Compounds Library Max

Related Products

Related compounds with same targets
NITD-916 Surfen dihydrochloride Delamanid Nourseothricin sulfate (6R,7S)-Cefminox sodium heptahydrate Brefeldin A Sertaconazole nitrate 1-Deoxynojirimycin hydrochloride

TargetMolDose Conversion

You can also refer to dose conversion for different animals. More

TargetMol In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

TargetMolCalculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Radezolid 869884-78-6 Microbiology/Virology Antibiotic Antibacterial inhibit Bacterial RX1741 Inhibitor RX 1741 RX-1741 inhibitor

 

TargetMol