Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 41.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone. |
Targets&IC50 | AChE:92.5 μmol/L(Zebrafish brain) |
In vivo | Zebrafish male adults were acutely exposed to 0.001, 0.01 and 0.1 μg/mL pyriproxyfen for 16 h. Mitochondrial respiration of brain tissues was assessed. ROS generation was estimated using H2DCF-DA and MitoSOX. Calcium transport was monitored by Calcium Green 5 N. NO synthesis activity was estimated using DAF-FM-DA. Brain acetylcholinesterase showed an in vivo IC20 of 0.30 μmol/L pyriproxyfen, and an IC50 of 92.5 μmol/L. The inhibitory effect on zbAChE activity was competitive-like. Respiratory control of Complex I/II decreased significantly after insecticide exposure. The MitoSOX test showed that O2- generation had a pyriproxyfen dose-dependent effect. Brain tissue lost 50% of Ca2+ uptake capacity at 0.1 μg/mL pyriproxyfen. Ca2+ release showed a clear mitochondrial impairment at lower pyriproxyfen exposures[1]. |
Synonyms | S-31183 |
Molecular Weight | 321.37 |
Formula | C20H19NO3 |
CAS No. | 95737-68-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (155.58 mM)
You can also refer to dose conversion for different animals. More
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Pyriproxyfen 95737-68-1 Others inhibit S-31183 Inhibitor Parasite Autophagy S31183 S 31183 inhibitor