Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Porfimer sodium is t he sodium salt of a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units with photodynamic activity. Absorbed selectively by tumor cells, porfimer produces oxygen radicals after activation by 630 nm wavelength laser light, resulting in tumor cell cytotoxicity. In addition, tumor cell death may occur due to ischemic necrosis secondary to vascular occlusion that appears to be partly mediated by the release of thromboxane A2.
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Description | Porfimer sodium is t he sodium salt of a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units with photodynamic activity. Absorbed selectively by tumor cells, porfimer produces oxygen radicals after activation by 630 nm wavelength laser light, resulting in tumor cell cytotoxicity. In addition, tumor cell death may occur due to ischemic necrosis secondary to vascular occlusion that appears to be partly mediated by the release of thromboxane A2. |
Synonyms | DHE, dihematoporphyrin ether, CL184116, CL-184116, CL 184116, Porfimer |
Molecular Weight | 1179.385 |
Formula | C68H74N8O11 |
CAS No. | 87806-31-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Porfimer Sodium 87806-31-3 DHE dihematoporphyrin ether CL184116 CL-184116 CL 184116 Porfimer inhibitor inhibit