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Platonin

Catalog No. T34086   CAS 3571-88-8
Synonyms: NK 19

Platonin is a therapeutic immunomodulating medicine and a possible medicine against ischemic stroke.

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Platonin Chemical Structure
Platonin, CAS 3571-88-8
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Platonin is a therapeutic immunomodulating medicine and a possible medicine against ischemic stroke.
Synonyms NK 19
Molecular Weight 909.91
Formula C38H61I2N3S3
CAS No. 3571-88-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Yeh CT, Kao MC, Chen CH, Huang CJ. Platonin preserves blood-brain barrier integrity in septic rats. Acta Anaesthesiol Taiwan. 2015 Mar;53(1):12-5. doi: 10.1016/j.aat.2015.02.001. Epub 2015 Mar 17. PubMed PMID: 25791838. 2. Peng TC, Chang CY, Huang IT, Kao MC, Chang YY, Huang CJ. Platonin mitigates vascular hyporeactivity of thoracic aorta in septic rats. J Surg Res. 2018 Jan;221:190-195. doi: 10.1016/j.jss.2017.08.054. Epub 2017 Sep 26. PubMed PMID: 29229127. 3. Sheu JR, Chen ZC, Jayakumar T, Chou DS, Yen TL, Lee HN, Pan SH, Hsia CH, Yang CH, Hsieh CY. A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice. Sci Rep. 2017 Feb 6;7:42277. doi: 10.1038/srep42277. PubMed PMID: 28165057; PubMed Central PMCID: PMC5292718. 4. Lee JJ, Chang CF, Sheu JR, Jayakumar T. Pharmacology and Clinical Effect of Platonin, a Cyanine Photosensitizing Dye: Potential Molecular Targets. Curr Pharm Biotechnol. 2014;15(8):700-11. PubMed PMID: 26050653.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Platonin 3571-88-8 NK 19 NK19 NK-19 inhibitor inhibit

 

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