Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity with Ki of 160 nM [1] [2] [3].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity with Ki of 160 nM [1] [2] [3]. |
In vitro | Phenyltoloxamine, within a concentration range of 10-50 μM over 24 hours, demonstrates cytotoxic effects on EVSA-T cells [2]. Additionally, it exhibits significant binding affinity for the Sigma 1 Receptor (S1R), with a K i value of 160 nM [3]. At a higher concentration of 100 μM, Phenyltoloxamine inhibits the CYP2D6 enzyme in human liver by 99.0% [4]. |
Molecular Weight | 255.35 |
Formula | C17H21NO |
CAS No. | 92-12-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Phenyltoloxamine 92-12-6 inhibitor inhibit