Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are <10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable. |
Molecular Weight | 382.87 |
Formula | C14H19ClN8OS |
CAS No. | 1305116-67-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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PF 04671536 hydrochloride 1305116-67-9 PF04671536 Hydrochloride PF-04671536 Hydrochloride PF 04671536 Hydrochloride inhibitor inhibit