Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-06445974 has good selectivity for PDE4D, excellent brain permeability, and has a high level of specific binding in the "cold tracer" study.
Description | PF-06445974 has good selectivity for PDE4D, excellent brain permeability, and has a high level of specific binding in the "cold tracer" study. |
Targets&IC50 | PDE4B:<1 nM (IC50), PDE4C:17 nM (IC50), PDE4A:4.7 nM (IC50), PDE4D:36 nM (IC50) |
Synonyms | PF-6445974, PF6445974, PF06445974, PF 6445974 |
Molecular Weight | 346.36 |
Formula | C20H15FN4O |
CAS No. | 2055776-17-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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PF-06445974 2055776-17-3 PF-6445974 PF6445974 PF06445974 PF 6445974 PF 06445974 inhibitor inhibit