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PD 142893

Catalog No. T25922 CAS 143037-36-9

Synonyms: PD-142893, PD142893

PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.

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PD 142893, CAS 143037-36-9

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.

Synonyms	PD-142893, PD142893
Molecular Weight	924.09
Formula	C50H65N7O10
CAS No.	143037-36-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Zimmermann M, Vatter H, Weyrauch E, Lange BN, Krishnan R, Raabe A, Seifert V. Characterization of the potent combined endothelin(A/B)-antagonist PD 142893 on cerebral vessels. Neurol Res. 2004 Sep;26(6):692-7. PubMed PMID: 15327761. 2. Warner TD, Allcock GH, Mickley EJ, Corder R, Vane JR. Comparative studies with the endothelin receptor antagonists BQ-123 and PD 142893 indicate at least three endothelin receptors. J Cardiovasc Pharmacol. 1993;22 Suppl 8:S117-20. PubMed PMID: 7509920. 3. Schroeder RL, Keiser JA, Cheng XM, Haleen SJ. PD 142893, SB 209670, and BQ 788 selectively antagonize vascular endothelial versus vascular smooth muscle ET(B)-receptor activity in the rat. J Cardiovasc Pharmacol. 1998 Dec;32(6):935-43. PubMed PMID: 9869499. 4. Warner TD, Allcock GH, Corder R, Vane JR. Use of the endothelin antagonists BQ-123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF. Br J Pharmacol. 1993 Oct;110(2):777-82. PubMed PMID: 8242251; PubMed Central PMCID: PMC2175921.

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Keywords

PD 142893 143037-36-9 PD-142893 PD142893 inhibitor inhibit

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