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Olanexidine Gluconate

Catalog No. T28230   CAS 799787-53-4
Synonyms: OPB2045G, OPB 2045, OPB-2045G, OPB2045, OPB-2045, OPB 2045G

Olanexidine gluconate is an antiseptic/disinfectant compound with potent bactericidal activity against Gram-negative and Gram-positive bacteria.

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Olanexidine Gluconate Chemical Structure
Olanexidine Gluconate, CAS 799787-53-4
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Olanexidine gluconate is an antiseptic/disinfectant compound with potent bactericidal activity against Gram-negative and Gram-positive bacteria.
Synonyms OPB2045G, OPB 2045, OPB-2045G, OPB2045, OPB-2045, OPB 2045G
Molecular Weight 568.49
Formula C23H39Cl2N5O7
CAS No. 799787-53-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Hagi A, Iwata K, Nii T, Nakata H, Tsubotani Y, Inoue Y. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59(8):4551-9. doi: 10.1128/AAC.05048-14. Epub 2015 May 18. PubMed PMID: 25987609; PubMed Central PMCID: PMC4505255. 2. Umehara K, Kudo S, Hirao Y, Morita S, Ohtani T, Uchida M, Miyamoto G. In vitro characterization of the oxidative cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes. Drug Metab Dispos. 2000 Dec;28(12):1417-24. PubMed PMID: 11095578. 3. Umehara K, Shimokawa Y, Koga T, Ohtani T, Miyamoto G. Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes. Xenobiotica. 2004 Jan;34(1):61-71. PubMed PMID: 14742137. 4. Kudo S, Umehara K, Morita S, Uchida M, Miyamoto G, Odomi M. Metabolism of 1-(3,4-dichlorobenzyl)-5-octylbiguanide in the dog. Xenobiotica. 1998 May;28(5):507-14. PubMed PMID: 9622852.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Olanexidine Gluconate 799787-53-4 OPB2045G OPB 2045 OPB-2045G OPB2045 OPB-2045 OPB 2045G inhibitor inhibit

 

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