Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells Δ7 5025 mouse myoblasts.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,820.00 | |
50 mg | 8-10 weeks | $ 2,380.00 | |
100 mg | 8-10 weeks | $ 3,100.00 |
Description | NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells Δ7 5025 mouse myoblasts. |
Targets&IC50 | SMN:5 nM (EC50) |
Molecular Weight | 406.52 |
Formula | C23H30N6O |
CAS No. | 1562333-92-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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NVS-SM2 1562333-92-9 NVS SM2 NVS-SM-2 NVSSM2 inhibitor inhibit