Powder: -20°C for 3 years | In solvent: -80°C for 1 year
High affinity α7 nAChR partial agonist (Ki = 1.1 nM in rat; Emax < 10% of the response to ACh in rat and human). Inhibits ACh (IC50 = 2.7 nM) at α7 nAChR. Reduces LPS-induced TNF-α release from microglia enriched cultures. Anti-inflammatory.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | Inquiry | $ 1,135.00 |
Description | High affinity α7 nAChR partial agonist (Ki = 1.1 nM in rat; Emax < 10% of the response to ACh in rat and human). Inhibits ACh (IC50 = 2.7 nM) at α7 nAChR. Reduces LPS-induced TNF-α release from microglia enriched cultures. Anti-inflammatory. |
Molecular Weight | 400.83 |
Formula | C19H20ClF3N2O2 |
CAS No. | 753499-14-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
You can also refer to dose conversion for different animals. More
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NS 6740 753499-14-8 NS-6740 NS6740 inhibitor inhibit