Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM) |
Targets&IC50 | α1-adrenoceptor (rat):237 nM (ki), D4 receptor:0.48 nM (ki), D3 receptor:39 nM (ki), 5-HT2A receptor:180 nM (Ki, in rat) |
In vivo | NRA0160 dose-dependently and significantly reverses the effects of MAP on both A9 and Al0 dopamine neurons.?NRA0160 is slightly more potent in reversiig the effects of MAP on A10 (ED50 = 1.0 mg/kg) than on A9 dopamine neurons (ED50 = 1.3 mg/kg).?NRA0160 reverses the effect of AP0 on both A9 and A10 dopamine neurons.?ED50 values for the effects of NRA0160 on APO-induced inhibition of A9 and A10 dopamine neurons are 1.3 mg/kg and 0.5 mg/kg, respectively[2]. |
Molecular Weight | 439.52 |
Formula | C24H23F2N3OS |
CAS No. | 204718-47-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NRA-0160 204718-47-8 GPCR/G Protein Neuroscience Dopamine Receptor NRA 0160 NRA0160 inhibitor inhibit