Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1]. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker used in antibody-drug conjugates(ADCs) synthesis[2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 29.00 |
Description | NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1]. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker used in antibody-drug conjugates(ADCs) synthesis[2]. |
In vitro | PROTACs, or proteolysis-targeting chimeras, are composed of two distinct ligands joined by a linker. One of these ligands binds to a specific protein target, while the other binds to an E3 ubiquitin ligase. When the PROTAC binds to both the target protein and the E3 ligase, it triggers the ubiquitin-proteasome system within cells to degrade the target protein, thereby providing a mechanism for targeted protein degradation. |
Molecular Weight | 409.51 |
Formula | C19H39NO8 |
CAS No. | 1286281-32-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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NH2-PEG6-Boc 1286281-32-0 PROTAC PROTAC Linker NH-2-PEG6-Boc inhibit ADC Linkers Antibody-drug conjugates linkers PROTAC Linkers Inhibitor NH2PEG6Boc NH2 PEG6 Boc inhibitor