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ND-336

Catalog No. T28146 CAS 1807453-83-3

Synonyms: ND336, ND-336 hydrochloride, ND 336

ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

ND-336, CAS 1807453-83-3

Pack Size	Availability	Price/USD
500 μg	35 days	$ 110.00
1 mg	35 days	$ 210.00
5 mg	35 days	$ 853.00
10 mg	35 days	$ 1,500.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
Targets&IC50	MMP2:85 nM (Ki), MMP9:150 nM (Ki), MMP14:120 nM (Ki)

Synonyms	ND336, ND-336 hydrochloride, ND 336
Molecular Weight	371.9
Formula	C16H18ClNO3S2
CAS No.	1807453-83-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Chang M. Restructuring of the extracellular matrix in diabetic wounds and healing: A perspective. Pharmacol Res. 2016 May;107:243-8. doi: 10.1016/j.phrs.2016.03.008. PubMed PMID: 27033051. 2. Jiang ZL, Sun YC, Wang ZB, Liang ZB, Ren K, Xie ZL, Zhang M, Liao Y. [Variation Characteristics and Sources of Polycyclic Aromatic Hydrocarbons in Karst Subterranean River During Rainfall Events]. Huan Jing Ke Xue. 2015 Nov;36(11):4088-94. Chinese. PubMed PMID: 26910994. 3. Gao M, Nguyen TT, Suckow MA, Wolter WR, Gooyit M, Mobashery S, Chang M. Acceleration of diabetic wound healing using a novel protease-anti-protease combination therapy. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15226-31. doi: 10.1073/pnas.1517847112. PubMed PMID: 26598687; PubMed Central PMCID: PMC4679041.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ND-336 1807453-83-3 ND 336 Hydrochloride ND336 ND-336 Hydrochloride ND336 Hydrochloride ND-336 hydrochloride ND 336 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.