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Milfasartan

Catalog No. T28039 CAS 148564-47-0

Synonyms: LR-B081, LRB-081, LR-B-081, LRB 081, LR-B 081

Milfasartan is a potent, selective antagonist of AT1 receptor with oral activity. It markedly lowers the blood-pressure in conscious renal and spontaneously hypertensive rats.

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Milfasartan, CAS 148564-47-0

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Milfasartan is a potent, selective antagonist of AT1 receptor with oral activity. It markedly lowers the blood-pressure in conscious renal and spontaneously hypertensive rats.

Synonyms	LR-B081, LRB-081, LR-B-081, LRB 081, LR-B 081
Molecular Weight	554.66
Formula	C30H30N6O3S
CAS No.	148564-47-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Soave R, Barzaghi M, Destro R. Progress in the understanding of drug-receptor interactions, part 2: experimental and theoretical electrostatic moments and interaction energies of an angiotensin II receptor antagonist (C30H30N6(O)3S). Chemistry. 2007;13(24):6942-56. PubMed PMID: 17539033. 2. Destro R, Soave R, Barzaghi M, Lo Presti L. Progress in the understanding of drug-receptor interactions, Part 1: experimental charge-density study of an angiotensin II receptor antagonist (C30H30N6O3S) at T = 17 K. Chemistry. 2005 Aug 5;11(16):4621-34. PubMed PMID: 15915518. 3. Noël B, Del Re G, Capone P, Brunner HR, Nussberger J. Clinical and hormonal effects of the new angiotensin II receptor antagonist LRB081. J Cardiovasc Pharmacol. 1996 Aug;28(2):252-8. PubMed PMID: 8856481. 4. Polidori C, Ciccocioppo R, Pompei P, Cirillo R, Massi M. Functional evidence for the ability of angiotensin AT1 receptor antagonists to cross the blood-brain barrier in rats. Eur J Pharmacol. 1996 Jul 4;307(3):259-67. PubMed PMID: 8836613.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Milfasartan 148564-47-0 LR-B081 LRB-081 LR-B-081 LRB 081 LR-B 081 LRB081 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.