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MZ 1

Catalog No. T5436   CAS 1797406-69-9

MZ 1 is a BRD4 protein degrader based on PROTAC technology.

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MZ 1 Chemical Structure
MZ 1, CAS 1797406-69-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 47.00
5 mg In stock $ 163.00
10 mg In stock $ 213.00
25 mg In stock $ 326.00
50 mg In stock $ 428.00
100 mg In stock $ 623.00
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Purity: 99.31%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description MZ 1 is a BRD4 protein degrader based on PROTAC technology.
Targets&IC50 BRD2 BD1/2:307/228 nM (Kd), BRD4 BD1/2:382/120 nM (Kd), BRD3 BD1/2:119/115 nM (Kd)
Molecular Weight 1002.64
Formula C49H60ClN9O8S2
CAS No. 1797406-69-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

TargetMolReferences and Literature

1. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 201. May;13(5):514-521.

Related compound libraries

This product is contained In the following compound libraries:
Kinase Inhibitor Library

Related Products

Related compounds with same targets
PBRM1-BD2-IN-2 PFI-3 MS436 Naphthol AS-E ML367 EML 425 MS31 trihydrochloride (2366264-12-0 free base) 3-methyl-1,2-dihydroquinolin-2-one

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MZ 1 1797406-69-9 Chromatin/Epigenetic Epigenetic Reader Domain cells protein Inhibitor Degrader PROTACs BRD4 selective degradation LS174t MZ-1 MZ1 inhibit inhibitor

 

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