Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MS117 is a first-in-class and cell-active irreversible covalent inhibitor of protein arginine methyltransferase 6 (PRMT6) (IC50 = 18 nM) [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 1,080.00 | |
50 mg | 10-14 weeks | $ 1,410.00 | |
100 mg | 10-14 weeks | $ 1,990.00 |
Description | MS117 is a first-in-class and cell-active irreversible covalent inhibitor of protein arginine methyltransferase 6 (PRMT6) (IC50 = 18 nM) [1]. |
In vitro | MS117 (Compound 4) selectively inhibits the activity of the PRMT6 methyltransferase in a time-dependent manner, exhibiting moderate 6-fold selectivity for PRMT6 over PRMT1 (IC50 = 0.1 ± 0.025 μM) and PRMT8 (IC50 = 0.11 ± 0.01 μM) [1]. |
Molecular Weight | 298.38 |
Formula | C17H22N4O |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.