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Lyngbyatoxin A

Catalog No. T33033 CAS 70497-14-2

Lyngbyatoxin A is an indole alkaloid from blue-green alga Lyngbya majuscula Gomont; responsible for dermatitis known as "swimmers' itch" in Hawaii.

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Lyngbyatoxin A, CAS 70497-14-2

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25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Lyngbyatoxin A is an indole alkaloid from blue-green alga Lyngbya majuscula Gomont; responsible for dermatitis known as "swimmers' itch" in Hawaii.

Molecular Weight	437.62
Formula	C27H39N3O2
CAS No.	70497-14-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Wells KN, Videau P, Nelson D, Eiting JE, Philmus B. The influence of sigma factors and ribosomal recognition elements on heterologous expression of cyanobacterial gene clusters in Escherichia coli. FEMS Microbiol Lett. 2018 Aug 1;365(15). doi: 10.1093/femsle/fny164. PubMed PMID: 29982530; PubMed Central PMCID: PMC6279124. 2. Zhang L, Hoshino S, Awakawa T, Wakimoto T, Abe I. Structural Diversification of Lyngbyatoxin A by Host-Dependent Heterologous Expression of the tleABC Biosynthetic Gene Cluster. Chembiochem. 2016 Aug 3;17(15):1407-11. doi: 10.1002/cbic.201600229. Epub 2016 Jun 17. PubMed PMID: 27194569. 3. Videau P, Wells KN, Singh AJ, Gerwick WH, Philmus B. Assessment of Anabaena sp. Strain PCC 7120 as a Heterologous Expression Host for Cyanobacterial Natural Products: Production of Lyngbyatoxin A. ACS Synth Biol. 2016 Sep 16;5(9):978-88. doi: 10.1021/acssynbio.6b00038. Epub 2016 Jun 1. PubMed PMID: 27176641. 4. Zhao Z, deMayo JA, West AM, Balunas MJ, Zweifach A. Development of an Enhanced Phenotypic Screen of Cytotoxic T-Lymphocyte Lytic Granule Exocytosis Suitable for Use with Synthetic Compound and Natural Product Collections. J Biomol Screen. 2016 Jul;21(6):556-66. doi: 10.1177/1087057116643260. Epub 2016 Apr 5. PubMed PMID: 27048485.

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