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Luxabendazole

Catalog No. T20960 CAS 90509-02-7

Synonyms: HOE 216V

Luxabendazole is a benzimidazole carbamate broad-spectrum anthelmintic agent. It has proved to be effective against immature and adult stages of the major gastrointestinal nematodes, cestodes, and trematodes.

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Luxabendazole, CAS 90509-02-7

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25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	HOE 216V
Molecular Weight	365.34
Formula	C15H12FN3O5S
CAS No.	90509-02-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Criado-Fornelio A, de Armas-Serra C, Jimenez-Gonzalez A, Casado-Escribano N, Rodriguez-Caabeiro F. Biochemical effects of luxabendazole on Trichinella spiralis. Parasitol Res. 1990;76(6):518-20. PubMed PMID: 2381894. 2. Kassai T, Takáts C, Fok E, Redl P. Activity of luxabendazole against liver flukes, gastrointestinal roundworms, and lungworms in naturally infected sheep. Parasitol Res. 1988;75(1):14-8. PubMed PMID: 2974592. 3. Ortiz AI, Alvarez-Bujidos L, Ferre I, Ordóñez D. Pharmacokinetics of luxabendazole after oral and intravenous administration to sheep. Am J Vet Res. 1997 Nov;58(11):1263-6. PubMed PMID: 9361890. 4. Alvarez-Bujidos ML, Ortiz A, Balaña R, Cubría JC, Ordoñez D, Negro A. Determination of luxabendazole in biological fluids by high-performance liquid chromatography. J Chromatogr. 1992 Jul 24;578(2):321-6. PubMed PMID: 1400814.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Luxabendazole 90509-02-7 HOE 216V inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.