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Lucidone

Catalog No. T20980 CAS 19956-53-7

Lucidone is a natural product with anti-inflammatory activity from Lindera erythrocarpa.

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Lucidone, CAS 19956-53-7

Pack Size	Availability	Price/USD	Quantity
5 mg	Inquiry	$ 1,489.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Lucidone is a natural product with anti-inflammatory activity from Lindera erythrocarpa.

Molecular Weight	256.26
Formula	C15H12O4
CAS No.	19956-53-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Chen WC, Wang SY, Chiu CC, Tseng CK, Lin CK, Wang HC, Lee JC. Lucidone suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction. Antimicrob Agents Chemother. 2013 Mar;57(3):1180-91. doi: 10.1128/AAC.02053-12. Epub 2012 Dec 17. PubMed PMID: 23254429; PubMed Central PMCID: PMC3591928. 2. Kumar KJ, Yang HL, Tsai YC, Hung PC, Chang SH, Lo HW, Shen PC, Chen SC, Wang HM, Wang SY, Chou CW, Hseu YC. Lucidone protects human skin keratinocytes against free radical-induced oxidative damage and inflammation through the up-regulation of HO-1/Nrf2 antioxidant genes and down-regulation of NF-κB signaling pathway. Food Chem Toxicol. 2013 Sep;59:55-66. doi: 10.1016/j.fct.2013.04.055. Epub 2013 May 24. PubMed PMID: 23712098. 3. Hsieh YH, Wang SY. Lucidone from Lindera erythrocarpa Makino fruits suppresses adipogenesis in 3T3-L1 cells and attenuates obesity and consequent metabolic disorders in high-fat diet C57BL/6 mice. Phytomedicine. 2013 Mar 15;20(5):394-400. doi: 10.1016/j.phymed.2012.11.007. Epub 2012 Dec 21. PubMed PMID: 23265843. 4. Senthil Kumar KJ, Liao JW, Xiao JH, Gokila Vani M, Wang SY. Hepatoprotective effect of lucidone against alcohol-induced oxidative stress in human hepatic HepG2 cells through the up-regulation of HO-1/Nrf-2 antioxidant genes. Toxicol In Vitro. 2012 Aug;26(5):700-8. doi: 10.1016/j.tiv.2012.03.012. Epub 2012 Mar 30. PubMed PMID: 22484158.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lucidone 19956-53-7 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.