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Lorcainide hydrochloride

Catalog No. T25757 CAS 58934-46-6

Synonyms: Ro 13-1042, EINECS 261-504-6, Lorcainide HCl, Lopantrol, R 15889

Lorcainide hydrochloride is an antiarrhythmic drug with local anesthetic activity. The antiarrhythmic actions of lorcainide are mediated by an impairment of fast sodium conductance. Lorcainide appears effective in suppressing reentry phenomena and ectopic pacemaker activity, especially in the ventricles.

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Lorcainide hydrochloride Chemical Structure

Lorcainide hydrochloride, CAS 58934-46-6

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Ro 13-1042, EINECS 261-504-6, Lorcainide HCl, Lopantrol, R 15889
Molecular Weight	407.38
Formula	C22H28Cl2N2O
CAS No.	58934-46-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Luo X, Zeng FD. [HPLC method for determination of lorcainide hydrochloride in human serum]. Yao Xue Xue Bao. 1995;30(8):605-9. Chinese. PubMed PMID: 8571780. 2. Somberg JC, Laux B, Wynn J, Keefe D, Miura DS. Lorcainide therapy in a cardiac arrest population. Am Heart J. 1986 Apr;111(4):648-53. PubMed PMID: 3953387. 3. Lauwers WF, Meuldermans WE, Bracke JO. Mass spectral investigation of the metabolites of lorcainide in man. Eur J Drug Metab Pharmacokinet. 1983 Oct-Dec;8(4):351-62. PubMed PMID: 6673972. 4. Shita A, Bernard R, Mostinckx R, Debacker M. Haemodynamic reactions after intravenous injection of lorcainide hydrochloride in acute myocardial infarction. Eur J Cardiol. 1981;12(5):237-42. PubMed PMID: 7250167.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lorcainide hydrochloride 58934-46-6 Ro 13-1042 EINECS 261-504-6 Lorcainide HCl Lorcainide Hydrochloride R-15889 Lopantrol R 15889 R15889 inhibitor inhibit

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