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Lonazolac Calcium

Catalog No. T27844 CAS 75821-71-5

Synonyms: Floxan, Irritren

Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.

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Lonazolac Calcium, CAS 75821-71-5

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25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.

Synonyms	Floxan, Irritren
Molecular Weight	354.85
Formula	C17H15CaClN2O2
CAS No.	75821-71-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Rubio Lotvin B, Ruíz Moreno JA, González Ansorena R, Ibarrola E, Uranga G, Benítez E. [Calcium lonazolac and blood loss in users of intrauterine devices. Preliminary report]. Ginecol Obstet Mex. 1986 Aug;54:221-4. Spanish. PubMed PMID: 3781294. 2. Deneke J, Luckow V, Guserle R, Pässler HH. Transsynovial kinetics of lonazolac and its hydroxy metabolite in synovitis patients. Int J Clin Pharmacol Ther. 1998 Aug;36(8):418-24. PubMed PMID: 9726694. 3. Raulf M, König W. Effects of the nonsteroidal anti-inflammatory compounds Lonazolac Ca, indomethacin and NDGA on inflammatory mediator generation and release from various cells. Immunopharmacology. 1990 Mar-Apr;19(2):103-11. PubMed PMID: 1693604. 4. Kullich W, Fromme K, Klein G. [Gastroduodenal tolerance and clinical effectiveness of therapy with lonazolac-calcium in rheumatic diseases]. Wien Med Wochenschr. 1996;146(17):459-64. German. PubMed PMID: 9045528.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lonazolac Calcium 75821-71-5 Floxan Irritren inhibitor inhibit

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