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Lolitrem B

Catalog No. T32851   CAS 81771-19-9

Lolitrem B is one of many toxins produced by a fungus called Epichloë festucae (var. lolii), which grows in perennial ryegrass. The fungus is symbiotic with the ryegrass; it doesn't harm the plant, and the toxins it produces kill insects that feed on ryegrass. Lolitrem B is one of these toxins, but it is also harmful to mammals.

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Lolitrem B Chemical Structure
Lolitrem B, CAS 81771-19-9
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25 mg Inquiry $ 1,520.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Lolitrem B is one of many toxins produced by a fungus called Epichloë festucae (var. lolii), which grows in perennial ryegrass. The fungus is symbiotic with the ryegrass; it doesn't harm the plant, and the toxins it produces kill insects that feed on ryegrass. Lolitrem B is one of these toxins, but it is also harmful to mammals.
Molecular Weight 685.902
Formula C42H55NO7
CAS No. 81771-19-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Repussard C, Zbib N, Tardieu D, Guerre P. Ergovaline and lolitrem B concentrations in perennial ryegrass in field culture in southern France: distribution in the plant and impact of climatic factors. J Agric Food Chem. 2014 Dec 31;62(52):12707-12. doi: 10.1021/jf504581y. Epub 2014 Dec 19. PubMed PMID: 25526521. 2. Johnstone LK, Mayhew IG. Flow-mediated K(+) secretion in horses intoxicated with lolitrem B (perennial ryegrass staggers). N Z Vet J. 2013 May;61(3):159-64. doi: 10.1080/00480169.2012.731682. Epub 2012 Nov 8. PubMed PMID: 23134178. 3. Shimada N, Yoshioka M, Mikami O, Tanimura N, Yamanaka N, Hanazumi M, Kojima F, Miyazaki S. Toxicological evaluation and bioaccumulation potential of lolitrem B, endophyte mycotoxin in Japanese black steers. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(8):1402-6. doi: 10.1080/19440049.2013.790090. Epub 2013 May 31. PubMed PMID: 23721156. 4. Johnstone LK, Mayhew IG, Fletcher LR. Clinical expression of lolitrem B (perennial ryegrass) intoxication in horses. Equine Vet J. 2012 May;44(3):304-9. doi: 10.1111/j.2042-3306.2011.00439.x. Epub 2011 Jul 27. PubMed PMID: 21793878.

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Keywords

Lolitrem B 81771-19-9 inhibitor inhibit

 

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