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Leucinostatin

Catalog No. T27816 CAS 39405-64-6

Synonyms: A 20668, A20668, A-20668

Leucinostatin is a peptide mycotoxins that have some potent effects on liver cells after oral administration. Leucinostatin is used as both antimicrobial and antitumor agents through interactions with the membrane phospholipids. Leucinostatin has shown effects against leukemia cell growth and prostate cancer cell growth.

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Leucinostatin, CAS 39405-64-6

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	A 20668, A20668, A-20668
Molecular Weight	1147.49
Formula	C58H102N10O13
CAS No.	39405-64-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Wang G, Liu Z, Lin R, Li E, Mao Z, Ling J, Yang Y, Yin WB, Xie B. Biosynthesis of Antibiotic Leucinostatins in Bio-control Fungus Purpureocillium lilacinum and Their Inhibition on Phytophthora Revealed by Genome Mining. PLoS Pathog. 2016 Jul 14;12(7):e1005685. doi: 10.1371/journal.ppat.1005685. eCollection 2016 Jul. PubMed PMID: 27416025; PubMed Central PMCID: PMC4946873. 2. Martinez AF, Moraes LA. Liquid chromatography-tandem mass spectrometry characterization of five new leucinostatins produced by Paecilomyces lilacinus CG-189. J Antibiot (Tokyo). 2015 Mar;68(3):178-84. doi: 10.1038/ja.2014.120. Epub 2014 Sep 3. PubMed PMID: 25182486. 3. Mikami Y, Fukushima K, Arai T, Abe F, Shibuya H, Ommura Y. Leucinostatins, peptide mycotoxins produced by Paecilomyces lilacinus and their possible roles in fungal infection. Zentralbl Bakteriol Mikrobiol Hyg A. 1984 Jul;257(2):275-83. PubMed PMID: 6485630. 4. Fukushima K, Arai T, Mori Y, Tsuboi M, Suzuki M. Studies on peptide antibiotics, leucinostatins. I. Separation, physico-chemical properties and biological activities of leucinostatins A and B. J Antibiot (Tokyo). 1983 Dec;36(12):1606-12. PubMed PMID: 6662804.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Leucinostatin 39405-64-6 A 20668 A20668 A-20668 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.