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Lemnalol

Catalog No. T25658 CAS 82570-34-1

Lemnalol is a natural marine compound from the Formosan soft coral Lemnalia cervicorni. It exhibits anti-inflammatory and analgesic effects in carrageenan-injected rats.

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Lemnalol, CAS 82570-34-1

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Lemnalol is a natural marine compound from the Formosan soft coral Lemnalia cervicorni. It exhibits anti-inflammatory and analgesic effects in carrageenan-injected rats.

Molecular Weight	220.356
Formula	C15H24O
CAS No.	82570-34-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Lee HP, Lin YY, Duh CY, Huang SY, Wang HM, Wu SF, Lin SC, Jean YH, Wen ZH. Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. J Pharm Pharmacol. 2015 Feb;67(2):274-85. doi: 10.1111/jphp.12331. Epub 2014 Dec 31. PubMed PMID: 25557511. 2. Lee HP, Huang SY, Lin YY, Wang HM, Jean YH, Wu SF, Duh CY, Wen ZH. Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression. Mar Drugs. 2013 Jan 10;11(1):99-113. doi: 10.3390/md11010099. PubMed PMID: 23306170; PubMed Central PMCID: PMC3564160. 3. Lin YC, Huang SY, Jean YH, Chen WF, Sung CS, Kao ES, Wang HM, Chakraborty C, Duh CY, Wen ZH. Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats. Behav Pharmacol. 2011 Dec;22(8):739-50. doi: 10.1097/FBP.0b013e32834d0ecb. PubMed PMID: 22067479. 4. Jean YH, Chen WF, Duh CY, Huang SY, Hsu CH, Lin CS, Sung CS, Chen IM, Wen ZH. Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni. Eur J Pharmacol. 2008 Jan 14;578(2-3):323-31. Epub 2007 Sep 20. PubMed PMID: 17916350.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lemnalol 82570-34-1 inhibitor inhibit

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