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Laserpitin

Catalog No. T32577 CAS 7067-12-1

Synonyms: NSC-109434, NSC 109434, NSC109434

Laserpitin is a coumarin compound from Angelica keiskei.

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Laserpitin, CAS 7067-12-1

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Laserpitin is a coumarin compound from Angelica keiskei.

Synonyms	NSC-109434, NSC 109434, NSC109434
Molecular Weight	450.572
Formula	C25H38O7
CAS No.	7067-12-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Ogawa H, Nakamura R, Baba K. Beneficial effect of laserpitin, a coumarin compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2005 Dec;32(12):1104-9. PubMed PMID: 16445577. 2. Shehzad O, Khan S, Ha IJ, Park Y, Tosun A, Kim YS. Application of stepwise gradients in counter-current chromatography: a rapid and economical strategy for the one-step separation of eight coumarins from Seseli resinosum. J Chromatogr A. 2013 Oct 4;1310:66-73. doi: 10.1016/j.chroma.2013.08.033. Epub 2013 Aug 16. PubMed PMID: 23992840. 3. Mohammadi M, Yousefi M, Habibi Z, Shafiee A. Two new coumarins from the chloroform extract of Angelica urumiensis from Iran. Chem Pharm Bull (Tokyo). 2010 Apr;58(4):546-8. PubMed PMID: 20410639. 4. Tosun A, Akkol EK, Yeşilada E. Anti-inflammatory and antinociceptive activity of coumarins from Seseli gummiferum subsp. corymbosum (Apiaceae). Z Naturforsch C. 2009 Jan-Feb;64(1-2):56-62. PubMed PMID: 19323267.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Laserpitin 7067-12-1 NSC-109434 NSC 109434 NSC109434 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.