Powder: -20°C for 3 years | In solvent: -80°C for 2 years
LY2444296 is an orally active and selective antagonist of kappa Opioid Receptor(Ki = 1 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 66.00 | |
10 mg | In stock | $ 124.00 | |
25 mg | In stock | $ 217.00 | |
50 mg | In stock | $ 315.00 |
Description | LY2444296 is an orally active and selective antagonist of kappa opioid receptor(Ki = 1 nM). |
Targets&IC50 | KOPR(ki):ki: ~1 nM |
In vivo | LY2444296 reduces anxiety-like and depressive-like behaviors, and CORT release, in rats tested after chronic extended access cocaine self-administration. In cocaine-naïve adult male Sprague Dawley rats, LY2444296 (3 mg/kg; i.p.) prevents behavioral and neuroendocrine effects caused by U69,593[2]. |
Synonyms | FP3FBZ |
Molecular Weight | 408.44 |
Formula | C24H22F2N2O2 |
CAS No. | 1346133-11-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
Ethanol: 25.2mg/mL (61.7mM), Need ultrasonic
Methanol: 5 mg/mL (12.24 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LY2444296 1346133-11-6 Endocrinology/Hormones GPCR/G Protein Neuroscience Opioid Receptor FP3FBZ inhibitor inhibit