Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC 50 of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 689.00 | |
50 mg | 6-8 weeks | $ 896.00 | |
100 mg | 6-8 weeks | $ 1,420.00 |
Description | LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC 50 of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders [1]. |
In vitro | LTA4H-IN-1 (15 min) inhibits the LTA4H-catalyzed hydrolysis of 7-amino-4-methylcoumarin (AMC) derivative of Arginine (Arg-AMC) with an IC 50 of 2 nM [1]. LTA4H-IN-1 (30 min) inhibits LTB4 biosynthesis in a human whole blood assay (hWB), with an IC 50 of 167 nM [1]. |
In vivo | LTA4H-IN-1 (0.3 mg/kg; a single p.o.) inhibits the -43% release of LTB4 compared to vehicle control in mice [1]. |
Synonyms | LYS-006 |
Molecular Weight | 392.77 |
Formula | C16H14ClFN6O3 |
CAS No. | 1799681-85-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LTA4H-IN-1 1799681-85-8 LTA4HIN1 LYS 006 LYS006 LYS-006 LTA-4H-IN-1 LTA4H IN 1 inhibitor inhibit