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L-Ibotenic acid

Catalog No. T25717 CAS 25690-45-3

Synonyms: Ibotenic acid, L-

L-Ibotenic acid is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere. It is a conformationally-restricted analog of the neurotransmitter glutamate, acts as a non-selective glutamate receptor agonist.

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L-Ibotenic acid, CAS 25690-45-3

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Ibotenic acid, L-
Molecular Weight	158.11
Formula	C5H6N2O4
CAS No.	25690-45-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Salzer HJF, Burchard G, Cornely OA, Lange C, Rolling T, Schmiedel S, Libman M, Capone D, Le T, Dalcolmo MP, Heyckendorf J. Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease. Respiration. 2018 Jun 28:1-19. doi: 10.1159/000489501. [Epub ahead of print] PubMed PMID: 29953992. 2. Bieleszová K, Pařízková B, Kubeš M, Husičková A, Kubala M, Ma Q, Sedlářová M, Robert S, Doležal K, Strnad M, Novák O, Žukauskaitė A. New fluorescently labeled auxins exhibit promising anti-auxin activity. N Biotechnol. 2018 Jun 25. pii: S1871-6784(17)30572-1. doi: 10.1016/j.nbt.2018.06.003. [Epub ahead of print] PubMed PMID: 29953966. 3. Frontiñan-Rubio J, Sancho-Bielsa FJ, Peinado JR, LaFerla FM, Giménez-Llort L, Durán-Prado M, Alcain FJ. Sex-dependent co-occurrence of hypoxia and β-amyloid plaques in hippocampus and entorhinal cortex is reversed by long-term treatment with ubiquinol and ascorbic acid in the 3 × Tg-AD mouse model of Alzheimer's disease. Mol Cell Neurosci. 2018 Jun 25. pii: S1044-7431(17)30154-9. doi: 10.1016/j.mcn.2018.06.005. [Epub ahead of print] PubMed PMID: 29953929. 4. Thomas DC. How the phagocyte NADPH oxidase regulates innate immunity. Free Radic Biol Med. 2018 Jun 25. pii: S0891-5849(18)31033-5. doi: 10.1016/j.freeradbiomed.2018.06.011. [Epub ahead of print] Review. PubMed PMID: 29953922.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

L-Ibotenic acid 25690-45-3 Ibotenic acid, L- LIbotenic acid L Ibotenic acid inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.