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L 640876

Catalog No. T24297 CAS 77527-71-0

Synonyms: L640,876, L-640876, L-640,876, L640876, L 640,876

L 640876 is a semisynthetic antibiotic.

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L 640876, CAS 77527-71-0

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

L 640876 is a semisynthetic antibiotic.

Synonyms	L640,876, L-640876, L-640,876, L640876, L 640,876
Molecular Weight	495.58
Formula	C22H21N7O3S2
CAS No.	77527-71-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Jacks TM, Schleim KD, Miller BM, Shungu DL, Weinberg E, Gadebusch HH. Quaternary heterocyclylamino beta-lactams. V. L-640,876 treatment of induced enterotoxigenic colibacillosis (scours) in calves and piglets. J Antibiot (Tokyo). 1983 Jan;36(1):70-5. PubMed PMID: 6381448. 2. Koupal LR, Pelak BA, Cassidy PJ, Gadebusch HH. Quaternary heterocyclylamino beta-lactams. III. The mode of action of L-640,876 and the effect of NaCl on membrane permeability and binding. J Antibiot (Tokyo). 1983 Jan;36(1):54-63. PubMed PMID: 6381447. 3. Celozzi E, Pelak BA, Stapley EO, Gadebusch HH. Quaternary heterocyclylamino beta-lactams. IV. Comparison of the in vivo antibacterial activities of L-640,876, mecillinam, cefoxitin and cefotaxime. J Antibiot (Tokyo). 1983 Jan;36(1):64-9. PubMed PMID: 6088459. 4. Koupal LR, Weissberger B, Shungu DL, Weinberg E, Gadebusch HH. Quaternary heterocyclylamino beta-lactams. II. The in vitro antibacterial properties of L-640,876, a new type of beta-lactam antibiotic. J Antibiot (Tokyo). 1983 Jan;36(1):47-53. PubMed PMID: 6088458.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

L 640876 77527-71-0 L640,876 L-640876 L-640,876 L640876 L 640,876 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.