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Kijanimicin

Catalog No. T25579 CAS 78798-08-0

Synonyms: Kijanimicin sodium salt

Kijanimicin is an antitumor and antibiotic. It is a unique, large acid enol antibiotic and possesses an unusual in vitro spectrum of activity against some Gram-positive and anaerobic microorganisms. It has also shown interesting activity against malaria in vivo.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Kijanimicin, CAS 78798-08-0

Pack Size	Availability	Price/USD	Quantity
500 μg	35 days	$ 880.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Kijanimicin sodium salt
Molecular Weight	1317.527
Formula	C67H100N2O24
CAS No.	78798-08-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Bradner WT, Claridge CA, Huftalen JB. Antitumor activity of kijanimicin. J Antibiot (Tokyo). 1983 Aug;36(8):1078-9. PubMed PMID: 6630059. 2. Waitz JA, Horan AC, Kalyanpur M, Lee BK, Loebenberg D, Marquez JA, Miller G, Patel MG. Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties. J Antibiot (Tokyo). 1981 Sep;34(9):1101-6. PubMed PMID: 7328052. 3. Zhang H, White-Phillip JA, Melançon CE 3rd, Kwon HJ, Yu WL, Liu HW. Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars. J Am Chem Soc. 2007 Nov 28;129(47):14670-83. Epub 2007 Nov 7. PubMed PMID: 17985890; PubMed Central PMCID: PMC2515274. 4. Cuthbertson L, Ahn SK, Nodwell JR. Deglycosylation as a mechanism of inducible antibiotic resistance revealed using a global relational tree for one-component regulators. Chem Biol. 2013 Feb 21;20(2):232-40. doi: 10.1016/j.chembiol.2012.11.011. PubMed PMID: 23438752.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molecular Weight Calculator

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Kijanimicin 78798-08-0 Kijanimicin sodium salt Kijanimicin sodium inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.