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Jurubidine

Catalog No. T32323 CAS 6084-44-2

Jurubidine is a type of cyclised aglycone from Jurubine.

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Jurubidine, CAS 6084-44-2

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Jurubidine is a type of cyclised aglycone from Jurubine.

Molecular Weight	415.65
Formula	C27H45NO2
CAS No.	6084-44-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Testi AM, Pession A, Diverio D, Grimwade D, Gibson B, de Azevedo AC, Moran L, Leverger G, Elitzur S, Hasle H, van der Werff Ten Bosch J, Smith O, De Rosa M, Piciocchi A, Lo Coco F, Foà R, Locatelli F, Kaspers GJL. Risk-adapted treatment of acute promyelocytic leukemia: results from International Consortium for Childhood APL. Blood. 2018 May 22. pii: blood-2018-03-836528. doi: 10.1182/blood-2018-03-836528. [Epub ahead of print] PubMed PMID: 29789356. 2. Correction: Daunorubicin reduces MBNL1 sequestration caused by CUG-repeat expansion and rescues cardiac dysfunctions in a Drosophila model of myotonic dystrophy (doi: 10.1242/dmm.032557). Dis Model Mech. 2018 May 18;11(5). pii: dmm035501. doi: 10.1242/dmm.035501. PubMed PMID: 29784710. 3. Karmo D, Hafeez A, Halalau A, Yadav S. Cardiac Tamponade as the Initial Presentation of Acute Myeloid Leukemia: A Case Report with Review of the Literature. Case Rep Oncol Med. 2018 Mar 26;2018:8201917. doi: 10.1155/2018/8201917. eCollection 2018. PubMed PMID: 29780652; PubMed Central PMCID: PMC5892271. 4. van Eijkelenburg NKA, Rasche M, Ghazaly E, Dworzak MN, Klingebiel T, Rossig C, Leverger G, Stary J, de Bont ESJM, Chitu DA, Bertrand Y, Brethon B, Strahm B, van der Sluis IM, Kaspers GJL, Reinhardt D, Zwaan CM. Clofarabine, high-dose cytarabine and liposomal daunorubicin in pediatric relapsed/refractory acute myeloid leukemia: a phase IB study. Haematologica. 2018 May 17. pii: haematol.2017.187153. doi: 10.3324/haematol.2017.187153. [Epub ahead of print] PubMed PMID: 29773602.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Jurubidine 6084-44-2 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.