Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNJ525 is an inhibitor of TNFα. JNJ525 inhibits protein function via an aggregation-based mechanism. JNJ525 prevents the formation of TNFα complexes with TNFR1 and TNFR2, the apparent IC50 values for the inhibition of complex formation are 1.2 ± 0.2 μM and 1.1 ± 0.1 μM respectively in the TR-FRET assay.
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Description | JNJ525 is an inhibitor of TNFα. JNJ525 inhibits protein function via an aggregation-based mechanism. JNJ525 prevents the formation of TNFα complexes with TNFR1 and TNFR2, the apparent IC50 values for the inhibition of complex formation are 1.2 ± 0.2 μM and 1.1 ± 0.1 μM respectively in the TR-FRET assay. |
Synonyms | JNJ 525, JNJ-525 |
Molecular Weight | 514.64 |
Formula | C31H30N8 |
CAS No. | T27687 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JNJ525 T27687 JNJ 525 JNJ-525 inhibitor inhibit