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Hydroxy ipronidazole

Catalog No. T24277 CAS 35175-14-5

Synonyms: L-12407, Ipronidazole-OH, L12407, L 12407

L 12407 is an antiprotozoal drug of the nitroimidazole class. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.

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Hydroxy ipronidazole, CAS 35175-14-5

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

L 12407 is an antiprotozoal drug of the nitroimidazole class. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.

Synonyms	L-12407, Ipronidazole-OH, L12407, L 12407
Molecular Weight	185.18
Formula	C7H11N3O3
CAS No.	35175-14-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Lin Z, Zhen Z, Chen C, Li Y, Luo C, Zhong L, Hu H, Li J, Zhang Y, Liang Y, Yang J, Zhang D. Rhizospheric effects on atrazine speciation and degradation in laterite soils of Pennisetum alopecuroides (L.) Spreng. Environ Sci Pollut Res Int. 2018 May;25(13):12407-12418. doi: 10.1007/s11356-018-1468-6. Epub 2018 Feb 19. PubMed PMID: 29460244. 2. Chen J, Qian Y, Li H, Cheng Y, Zhao M. The reduced bioavailability of copper by nano-TiO₂ attenuates the toxicity to Microcystis aeruginosa. Environ Sci Pollut Res Int. 2015 Aug;22(16):12407-14. doi: 10.1007/s11356-015-4492-9. Epub 2015 Apr 23. PubMed PMID: 25903177. 3. Das LK, Kadam RM, Bauzá A, Frontera A, Ghosh A. Differences in nuclearity, molecular shapes, and coordination modes of azide in the complexes of Cd(II) and Hg(II) with a "metalloligand" [CuL] (H2L = N,N'-bis(salicylidene)-1,3-propanediamine): characterization in solid and in solutions, and theoretical calculations. Inorg Chem. 2012 Nov 19;51(22):12407-18. doi: 10.1021/ic301773h. Epub 2012 Nov 6. PubMed PMID: 23131113. 4. Klein RR, Bourdon DM, Costales CL, Wagner CD, White WL, Williams JD, Hicks SN, Sondek J, Thakker DR. Direct activation of human phospholipase C by its well known inhibitor u73122. J Biol Chem. 2011 Apr 8;286(14):12407-16. doi: 10.1074/jbc.M110.191783. Epub 2011 Jan 25. PubMed PMID: 21266572; PubMed Central PMCID: PMC3069444.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Hydroxy ipronidazole 35175-14-5 L-12407 Ipronidazole-OH L12407 L 12407 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.