keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Selective NaV1.7 channel blocker. Preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = <10 μM). Inhibits the channel by binding at the neurotoxin receptor site 4 in the S3-S4 linker of domain II, trapping the voltage sensor in the inward, closed configuration.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | Inquiry | $ 614.00 |
Description | Selective NaV1.7 channel blocker. Preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM). Inhibits the channel by binding at the neurotoxin receptor site 4 in the S3-S4 linker of domain II, trapping the voltage sensor in the inward, closed configuration. |
Synonyms | Huwentoxin IV |
Molecular Weight | 4106.79 |
Formula | C174H278N52O51S6 |
CAS No. | 526224-73-7 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 1 mg/mL
You can also refer to dose conversion for different animals. More
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Huwentoxin-IV 526224-73-7 HuwentoxinIV Huwentoxin IV inhibitor inhibit