Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 98.00 | |
10 mg | In stock | $ 178.00 | |
25 mg | In stock | $ 397.00 | |
50 mg | In stock | $ 589.00 | |
100 mg | In stock | $ 843.00 | |
500 mg | In stock | $ 1,730.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 116.00 |
Description | H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment. |
Targets&IC50 | LPA 2 Receptor:9 nM (IC50) |
In vitro | The high cell invasion activity of HT1080-M6 cells is significantly suppressed by H2L5186303[1]. |
In vivo | H2L5186303 shows strong suppressive efficacy when administered before OVA sensitization and challenge, such as suppression of airway hyper responsiveness, inflammatory cytokine levels, mucin production, and eosinophil numbers[2]. |
Synonyms | ZINC33388081 |
Molecular Weight | 488.45 |
Formula | C26H20N2O8 |
CAS No. | 139262-76-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 200 mg/mL (409.5 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
H2L5186303 139262-76-3 GPCR/G Protein LPA Receptor H2L-5186303 ZINC-33388081 H2L 5186303 ZINC33388081 ZINC 33388081 inhibitor inhibit