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Grosvenorine

Catalog No. TN1714 CAS 156980-60-8

Synonyms: Grosvenorin

Grosvenorine (Grosvenorin) exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities.

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Grosvenorine, CAS 156980-60-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 106.00
5 mg	In stock	$ 257.00
10 mg	In stock	$ 380.00
25 mg	In stock	$ 638.00
50 mg	In stock	$ 890.00
100 mg	In stock	$ 1,230.00
1 mL * 10 mM (in DMSO)	In stock	$ 390.00

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Purity: 99.6%

Purity: 97.40%

Biological Description

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Storage & Solubility Information

Description	Grosvenorine (Grosvenorin) exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities.
In vitro	The Grosvenorine metabolism in an in vitro simulated human gastrointestinal tract (including artificial gastric juice, artificial intestinal juice and intestinal flora), as well as its pharmacological activities (including anti-complement, antibacterial and antioxidant activities), was investigated. The results showed that Grosvenorine was metabolized by human intestinal flora; its four metabolites were isolated by semi-preparative HPLC and identified by NMR as kaempferitrin, afzelin, α±-rhamnoisorobin, and kaempferol. Further pharmacological evaluation showed that Grosvenorine exhibited good antibacterial and antioxidant activities, with its metabolites possessing more potent activities. Although Grosvenorine did not present obvious anticomplement activity, its metabolites showed interesting activities.
Source	Natural Products > Cucurbitaceae > Siraitia

Synonyms	Grosvenorin
Molecular Weight	740.66
Formula	C33H40O19
CAS No.	156980-60-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (67.5 mM)

References and Literature

1. The Gastrointestinal Tract Metabolism and Pharmacological Activities of Grosvenorine, a Major and Characteristic Flavonoid in the Fruits of Siraitia grosvenorii.Chem Biodivers. 2015 Nov;12(11):1652-64.

Related compound libraries

This product is contained In the following compound libraries：

Polyphenolic Natural Product Library Anti-infective Natural Product Library Food as Medicine Compound Library Anti-Bacterial Compound Library Anti-Gastroenteritis Natural Product Library Chinese Pharmacopoeia Natural Product Library Antioxidant Compound Library Ferroptosis Compound Library Traditional Chinese Medicine Monomer Library Bioactive Compound Library

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Keywords

Grosvenorine 156980-60-8 Microbiology/Virology Antibacterial Bacterial inhibit Inhibitor Grosvenorin inhibitor

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