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Metabolism FXR Glyco-Obeticholic acid

Glyco-Obeticholic acid

Catalog No. T11428   CAS 863239-60-5

Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).

Glyco-Obeticholic acid, CAS 863239-60-5
Pack Size Availability Price/USD Quantity
1 mg In stock 164.00
5 mg In stock 322.00
10 mg In stock 485.00
25 mg In stock 870.00
50 mg In stock 1304.00
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Purity 99.95%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).
Targets&IC50 Others
In vitro Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces.
Molecular Weight 477.68
Formula C28H47NO5
CAS No. 863239-60-5

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6.

Related Products

Related compounds with same targets
Gly-β-MCA Glyco-Obeticholic acid (-)-PX20606 trans isomer Tauro-Obeticholic acid Tauro-β-muricholic acid sodium LY2562175 LY367385 Obeticholic Acid

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