Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective inhibitor of cyclin G associated kinase (GAK) with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride can also bind to RIPK2.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | 10-14 weeks | $ 1,110.00 | |
200 mg | 10-14 weeks | $ 1,690.00 |
Description | GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective inhibitor of cyclin G associated kinase (GAK) with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride can also bind to RIPK2. |
In vitro | GAK inhibitor 49 (compound 49) hydrochloride demonstrates limited inhibition towards AAK1, BMP2K, and STK16, exhibiting IC50 values of 28, 63, and >100μM, respectively [1]. |
Molecular Weight | 406.86 |
Formula | C20H23ClN2O5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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GAK inhibitor 49 hydrochloride inhibitor inhibit