Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GABAA Receptor Agent 5 (compound 018) serves as a potent γ-GABAAR antagonist, possessing a Ki of 0.020 μM. This compound exhibits γ-GABAAR antagonist properties, yet it demonstrates low cellular membrane permeability [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | GABAA Receptor Agent 5 (compound 018) serves as a potent γ-GABAAR antagonist, possessing a Ki of 0.020 μM. This compound exhibits γ-GABAAR antagonist properties, yet it demonstrates low cellular membrane permeability [1]. |
In vitro | Compound 018, a GABAA receptor agent, exhibits antagonist activity, demonstrated by its IC50 values. These are 0.24 μM for α1β2δ, 0.088 μM for α4β1δ, 0.068 μM for α4β2δ, 0.33 μM for α6β2δ, 0.79 μM for α1β2γ2, 0.32 μM for α2β2γ2, 0.079 μM for α3β2γ2, and 0.051 μM for α5β2γ2 subtypes, respectively [1]. |
Molecular Weight | 383.51 |
Formula | C21H25N3O2S |
CAS No. | 1808389-92-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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GABAA receptor agent 5 1808389-92-5 inhibitor inhibit