Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 101.00 | |
25 mg | In stock | $ 181.00 | |
50 mg | In stock | $ 328.00 | |
100 mg | In stock | $ 571.00 | |
500 mg | In stock | $ 1,250.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 75.00 |
Description | FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM). |
Targets&IC50 | Notch:2.3 μM(EC50) |
Kinase Assay | EC50 values of the test compounds are calculated from serial dilution series ranging from 200 to 0.1 μM. Cells are seeded in 96-well plates at a density of 5,000 cells per well in 100 μL medium. The next day, 100 μL medium containing each test compound is added. Cells are incubated for 16 h, fixed and processed for automated microscopy. EC50 estimates are calculated using four-parameter log-logistic fit with the package drc[1]. |
Synonyms | FLI 06 |
Molecular Weight | 438.52 |
Formula | C25H30N2O5 |
CAS No. | 313967-18-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 8.8 mg/mL (20 mM)
DMSO: 43.9 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
FLI-06 313967-18-9 Neuroscience Proteases/Proteasome Stem Cells Gamma-secretase inhibit Inhibitor Notch FLI 06 FLI06 inhibitor