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Duazomycin

Catalog No. T27217 CAS 2508-89-6

Synonyms: Duazomycin A, Acetyl-don, Diazomycin A, NSC 51097

Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Duazomycin, CAS 2508-89-6

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.

Synonyms	Duazomycin A, Acetyl-don, Diazomycin A, NSC 51097
Molecular Weight	213.19
Formula	C8H11N3O4
CAS No.	2508-89-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. ROSENBERG S, CALABRESI P. ENHANCED SUPPRESSION OF THE SECONDARY IMMUNE RESPONSE BY COMBINATION OF 6-MERCAPTOPURINE DUAZOMYCIN A'. Nature. 1963 Sep 14;199:1101-2. PubMed PMID: 14066954. 2. Kaplan SR, Hayslett JP, Calabresi P. Treatment of advanced Wegener's granulomatosis with azathioprine and duazomycin A. N Engl J Med. 1968 Feb 1;278(5):239-44. PubMed PMID: 5635457. 3. Vogel CL, Calabresi P. Enhanced suppression of experimental allergic encephalomyelitis by combination chemotherapy with duazomycin-A and 6-mercaptopurine. Proc Soc Exp Biol Med. 1969 May;131(1):251-6. PubMed PMID: 5770114. 4. Foley HT, Shnider BI, Gold GL, Rius J. A pilot study of methotrexate, duazomycin A, and radiation therapy in carcinoma of the lung. J New Drugs. 1966 Mar-Apr;6(2):105-11. PubMed PMID: 5331283.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Duazomycin 2508-89-6 Duazomycin A NSC-51097 Acetyl-don NSC51097 Diazomycin A NSC 51097 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.