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Dexamethasone phosphate

Catalog No. T23984   CAS 312-93-6
Synonyms: Neodecadron, EGP437, Hexadrol phosphate, EGP 437, EGP-437

Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.

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Dexamethasone phosphate Chemical Structure
Dexamethasone phosphate, CAS 312-93-6
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.
Synonyms Neodecadron, EGP437, Hexadrol phosphate, EGP 437, EGP-437
Molecular Weight 472.44
Formula C22H30FO8P
CAS No. 312-93-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Sharma AK, Sharma HR, Sharma R, Singh A. Comparison of Preoperative Topical Dexamethasone Phosphate Versus Ketorolac Tromethamine in Maintaining Intraoperative Mydriasis During Small Incision Cataract Surgery. J Clin Diagn Res. 2016 May;10(5):NC09-13. doi: 10.7860/JCDR/2016/19590.7863. Epub 2016 May 1. PubMed PMID: 27437255; PubMed Central PMCID: PMC4948431. 2. Torres MP, Entwistle F, Coote PJ. Effective immunosuppression with dexamethasone phosphate in the Galleria mellonella larva infection model resulting in enhanced virulence of Escherichia coli and Klebsiella pneumoniae. Med Microbiol Immunol. 2016 Aug;205(4):333-43. doi: 10.1007/s00430-016-0450-5. Epub 2016 Feb 26. PubMed PMID: 26920133; PubMed Central PMCID: PMC4939170. 3. Martín-Sabroso C, Tavares-Fernandes DF, Espada-García JI, Torres-Suárez AI. Validation protocol of analytical procedures for quantification of drugs in polymeric systems for parenteral administration: dexamethasone phosphate disodium microparticles. Int J Pharm. 2013 Dec 15;458(1):188-96. doi: 10.1016/j.ijpharm.2013.09.026. Epub 2013 Oct 9. PubMed PMID: 24120930. 4. Patane MA, Schubert W, Sanford T, Gee R, Burgos M, Isom WP, Ruiz-Perez B. Evaluation of ocular and general safety following repeated dosing of dexamethasone phosphate delivered by transscleral iontophoresis in rabbits. J Ocul Pharmacol Ther. 2013 Oct;29(8):760-9. doi: 10.1089/jop.2012.0175. Epub 2013 Jul 11. PubMed PMID: 23844757.

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Keywords

Dexamethasone phosphate 312-93-6 Neodecadron Dexamethasone Phosphate EGP437 Hexadrol Phosphate Hexadrol phosphate EGP 437 EGP-437 inhibitor inhibit

 

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