Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.48.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 213.00 | |
50 mg | In stock | $ 378.00 | |
100 mg | In stock | $ 562.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.48. |
Targets&IC50 | nAChR:6.48(pEC50) |
In vitro |
Desformylflustrabromine hydrochloride potentiates ACh-induced responses of wild-type receptors expressed using the HS isoform preparation maximally by 350±20%, which is similar to receptors expressed via the LS isoform preparation (350±30%).[2] ACh-induced currents are potentiated and inhibited by Desformylflustrabromine hydrochloride in the high sensitivity (HS) and low sensitivity (LS) isoform preparations, although Desformylflustrabromine hydrochloride displays a higher potency on the LS isoform (pEC50=6.4±0.2) compare with the HS isoform (pEC50=5.6±0.2).[2] |
Synonyms | dFBr hydrochloride, Deformylflustrabromine hydrochloride |
Molecular Weight | 437.19 |
Formula | C17H12INO5 |
CAS No. | 951322-11-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 4.5 mg/mL (12.6 mM), Sonification is recommended.
DMSO: 94.5 mg/mL (264.2 mM)
You can also refer to dose conversion for different animals. More
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Desformylflustrabromine hydrochloride 951322-11-5 Neuroscience AChR dFBr hydrochloride dFBr Hydrochloride Deformylflustrabromine hydrochloride Deformylflustrabromine Hydrochloride Desformylflustrabromine Hydrochloride inhibitor inhibit