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Dehydroisoandrosterone 3-acetate

Catalog No. T0856 CAS 853-23-6

Synonyms: Dehydroepiandrosterone 3-acetate, Dehydroepiandrosterone acetate, Prasterone acetate, DHEA acetate, androstenolone acetate

Dehydroisoandrosterone 3-acetate (Prasterone acetate) is a primary C19 steroid generated by the adrenal cortex.

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Dehydroisoandrosterone 3-acetate Chemical Structure

Dehydroisoandrosterone 3-acetate, CAS 853-23-6

Pack Size	Availability	Price/USD
500 mg	In stock	$ 41.00
1 g	In stock	$ 48.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 100%

Purity: 99.81%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Dehydroisoandrosterone 3-acetate (Prasterone acetate) is a primary C19 steroid generated by the adrenal cortex.

In vivo

Dehydroisoandrosterone 3-acetate implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of birds implanted with Dehydroisoandrosterone 3-acetate display higher aromatase mRNA expression in the preoptic area (POA) as well as higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone 3-acetate -induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone 3-acetate levels[1]. Dehydroisoandrosterone 3-acetate supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group[2].

Synonyms	Dehydroepiandrosterone 3-acetate, Dehydroepiandrosterone acetate, Prasterone acetate, DHEA acetate, androstenolone acetate
Molecular Weight	330.46
Formula	C21H30O3
CAS No.	853-23-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 9 mg/mL (27.23 mM)

References and Literature

1. Wacker DW, et al. Dehydroepiandrosterone (DHEA) heightens aggression and increases androgen receptor and aromatase mRNA expression in the brain of a male songbird. J Neuroendocrinol. 2016 Nov 2. 2. Chen WC, et al. Dehydroepiandrosterone Supplementation Combined with Whole-Body Vibration Training Affects Testosterone Level and Body Composition in Mice. Int J Med Sci. 2016 Sep 16;13(10):730-740.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Approved Drug Library Drug Repurposing Compound Library Anti-Cancer Drug Library NO PAINS Compound Library FDA-Approved & Pharmacopeia Drug Library Orally Active Compound Library Bioactive Compound Library FDA-Approved Drug Library Anti-Prostate Cancer Compound Library Natural Product Library for HTS

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Keywords

Dehydroisoandrosterone 3-acetate 853-23-6 Endocrinology/Hormones Androgen Receptor DHEA Dehydroepiandrosterone 3-acetate Dehydroisoandrosterone 3 acetate Dehydroepiandrosterone Acetate Dehydroepiandrosterone acetate Dehydroisoandrosterone 3acetate androstenolone Acetate Prasterone acetate Prasterone Acetate Inhibitor DHEA acetate Dehydroisoandrosterone androstenolone acetate inhibit Dehydroepiandrosterone DHEA Acetate inhibitor

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