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Deacetyl-N,O-didemethyldiltiazem

Catalog No. T31247 CAS 86408-42-6

Deacetyl-N,O-didemethyldiltiazem is a biochemical.

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Deacetyl-N,O-didemethyldiltiazem Chemical Structure

Deacetyl-N,O-didemethyldiltiazem, CAS 86408-42-6

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Deacetyl-N,O-didemethyldiltiazem is a biochemical.

Molecular Weight	344.43
Formula	C18H20N2O3S
CAS No.	86408-42-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Zarev Y, Foubert K, Ionkova I, Apers S, Pieters L. Isolation and Structure Elucidation of Glucosylated Colchicinoids from the Seeds of Gloriosa superba by LC-DAD-SPE-NMR. J Nat Prod. 2017 Apr 28;80(4):1187-1191. doi: 10.1021/acs.jnatprod.6b01024. Epub 2017 Feb 17. PubMed PMID: 28211687. 2. Kumbhar BV, Borogaon A, Panda D, Kunwar A. Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations. PLoS One. 2016 May 26;11(5):e0156048. doi: 10.1371/journal.pone.0156048. eCollection 2016. PubMed PMID: 27227832; PubMed Central PMCID: PMC4882049. 3. Ho CT, Chang YJ, Yang LX, Wei PL, Liu TZ, Liu JJ. A Novel Microtubule-Disrupting Agent Induces Endoplasmic Reticular Stress-Mediated Cell Death in Human Hepatocellular Carcinoma Cells. PLoS One. 2015 Sep 10;10(9):e0136340. doi: 10.1371/journal.pone.0136340. eCollection 2015. PubMed PMID: 26355599; PubMed Central PMCID: PMC4565632. 4. Ab O, Whiteman KR, Bartle LM, Sun X, Singh R, Tavares D, LaBelle A, Payne G, Lutz RJ, Pinkas J, Goldmacher VS, Chittenden T, Lambert JM. IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors. Mol Cancer Ther. 2015 Jul;14(7):1605-13. doi: 10.1158/1535-7163.MCT-14-1095. Epub 2015 Apr 22. PubMed PMID: 25904506.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Deacetyl-N,O-didemethyldiltiazem 86408-42-6 Deacetyl N,O didemethyldiltiazem DeacetylN,Odidemethyldiltiazem inhibitor inhibit

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